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|Product Name:||YK-11||Other Name:||Myostatin Inhibito|
99% Purity SARM Steroids YK-11 Prohormone SARMS Myostatin Inhibito 431579-34-9
SARMS or selective androgen receptor modulators are well-known for giving the same muscle growth results as anabolic steroids but without the negative side effects that comes with the latter.
Japanese scientists are doing an experiment on a new SARM known as YK11 which is said to be the strongest amongst all, even more potent than classic steroids such as DHT. YK11 is believed to be a SARM and produce the effect of myostatin at the same time.
YK11 is a potent and specific synthetic REV-ERB. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism.
Administration of YK11 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice.
The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with YK11 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia.
These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
Usage: Sarms, Bodybuilding
|ANALYTICAL ITEMS||SPECIFICATION||ANALYTICAL RESULTS|
|Appearance||White Powder||White powder|
|Related substances||A single impurity≤0.5%||0.18%|
|Loss on drying||≤0.5%||0.18%|
|Conclusion||Confirms to Enterprise Standard|
YK11 shows a lot of promise as an apt anabolic SARM. With the muscle growth potential it brings, it's as effective as anabolic steroids and prohormones without the unwanted side effects connected to the latter.
1. MUSCLE STRENGTH:
in the report of Kanno, muscle cells exposed to it creates more anabolic effects than those exposed with DHT. On that note, it can be safe to say that it is best for muscle strengthening,
without the detrimental effects caused by traditional steroids,including many health risks. What takes place is that it induces muscle cells, stimulating them to create a greater number of follistatin, much better than DHT.
Additionally, it cannot be ignored that this research chemical, being a SARM works through the muscle's androgen receptors but does not harm the bones and joints and other body parts where ARs are found-due to its SELECTIVE ACTIVITY.
2. MYOSTAT ININHIBITOR:
While YK-11 has been proven to work as a great supplement for building muscle strength, especially ideal for bodybuilders and athletes, it is also found to be a great myostatin inhibitor. It is special and valuableas a SARM that acts as a strong androgen but without the side effects you will commonly experience from injectable alternatives, like steroids and prohormones.
It also works as a myostatin inhibitor. What is myostatin, anyway? This is a type of protein that limits the production and the growth of the muscle tissues, when it is present. So by inhibiting myostatin action, you can actually improve your body's potential to build bigger and leaner muscle tissue. But while it sounds too good to be true, it has been proven by the scientists themselves.
What happens is that it also inhibits the production and gradually deactivates follistatin, a myostatin inhibitor. On that note, it can be told that it is a potent and effective myostatin inhibitor aside from its anabolic properties, which means more muscle for you!
3. MUSCLE GROWTH:
YK11 can be taken at doses between 5 and 8 mg per day at an eight-week cycle. However, you may be concerned about estrogen effects, including breast enlargements, but that's now out of the picture.
Because of its selective characteristic, it does what it does very well but only on the anabolic activity of the muscle cells for muscle growth without the adverse estrogen effects, which may cause you humiliation for sporting
Additionally,this compound does not alter the expression of other genes in the body because it leaves out the androgen receptors in other body parts, including the bones, joints and prostate. Therefore, you can experience great muscle building benefits, except the side effects you might have to face if you would choose typical steroids on the market.
The best part is that it delivers all the above-mentioned benefits without harming your body, especially your liver-something that you might have to deal with by choosing other prohormones on the market, which may require longer use before any dramatic results can be achieved.
Since studies are still underway and conclusive details about the compound are yet to be published, side effects cannot be noted at this moment.Based on logs and initial findings, there are no adverse effects noted at all.
In direct comparison to to LGD-4033 as the reference for assay upon animal models of anabolism and androgenicity, YK-11 demonstrated higher efficacy withing anabolic parameters and lesser androgenicity at equivalent dosages.
It induces muscle cells to make more follistatin which is a strong myostatin inhibitor. Myostatin (also known as growth differentiation factor 8, is a myokine (protein) produced by muscle cells that acts on muscle cells to inhibit myogenesis. Myogenesis is muscle cell growth and differentiation. Research through the years show that when you block myostatin, it allows for significantly more muscle mass. So in research myostatin inhibitors are researched to find cures for muscle diseases.
We expect YK11 to be more potent than SARM LGD in terms of overall growth and feel. At this time, we expect this to be the strongest SARM on the market at a regular dosing. While suppression can occur, we expect this product to have low androgenic properties and can be used by both men and women. From our experience with SARMs, we find there are less losses of on-cycle results than pro-hormones, although typically not as potent. We do expect this product to have similar results as a moderately dosed Halodrol, without the alpha-male/androgenic feelings while on it.
Dosages and Suggestion
Recommended maximum dose YK11 is require dosages of 2.0-5.0mg b.i.d. in males and 0.5mg-2mg b.i.d. in females to achieve optimal effects in humans for the noted indications.